The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2016

Filed:

Aug. 24, 2012
Applicants:

Rodney Kiplin Guy, Memphis, TN (US);

Fangyi Zhu, Memphis, TN (US);

Wendyam Armand Guiguemde, Memphis, TN (US);

David Floyd, Pennington, NJ (US);

Spencer Knapp, Skillman, NJ (US);

Philip Stein, Pennington, NJ (US);

Steve Castro, East Hannover, NJ (US);

Inventors:

Rodney Kiplin Guy, Memphis, TN (US);

Fangyi Zhu, Memphis, TN (US);

Wendyam Armand Guiguemde, Memphis, TN (US);

David Floyd, Pennington, NJ (US);

Spencer Knapp, Skillman, NJ (US);

Philip Stein, Pennington, NJ (US);

Steve Castro, East Hannover, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 409/04 (2006.01); C07D 417/04 (2006.01); A61K 31/4725 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61K 31/4725 (2013.01); A61K 31/506 (2013.01); A61K 45/06 (2013.01); C07D 409/04 (2013.01); C07D 417/04 (2013.01);
Abstract

In one aspect, the invention relates to novel substituted 2-alkyl-1-oxo-N-phenyl-3-heteroaryl -1,2,3,4-tetrahydroisoquinoline-4-carboxamides; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating and/or preventing malaria. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.


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