The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2016

Filed:

May. 23, 2014
Applicant:

Warsaw Orthopedic, Inc., Warsaw, IN (US);

Inventors:

Keyvan Behnam, Red Bank, NJ (US);

Nanette Forsyth, Bayville, NJ (US);

James Russell, Little Silver, NJ (US);

John Winterbottom, Howell, NJ (US);

Todd Boyce, Matawan, NJ (US);

Assignee:

Warsaw Orthopedic, Inc., Warsaw, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/36 (2006.01); A61F 2/28 (2006.01); A61L 27/38 (2006.01); A61K 35/32 (2015.01); A61F 2/30 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3687 (2013.01); A61K 35/32 (2013.01); A61L 27/3608 (2013.01); A61L 27/3641 (2013.01); A61L 27/3645 (2013.01); A61L 27/3683 (2013.01); A61L 27/3691 (2013.01); A61L 27/3695 (2013.01); A61L 27/3878 (2013.01); A61F 2/28 (2013.01); A61F 2002/2817 (2013.01); A61F 2002/30059 (2013.01); A61F 2310/00359 (2013.01); A61L 2430/02 (2013.01);
Abstract

An osteoinductive demineralized bone matrix, corresponding osteoimplants, and methods for making the osteoinductive demineralized bone matrix are disclosed. The osteoinductive demineralized bone matrix may be prepared by providing demineralized bone and altering the collagenous structure of the bone. The osteoinductive demineralized bone matrix may also be prepared by providing demineralized bone and compacting the bone, for example via mechanical compaction, grinding into a particulate, or treatment with a chemical. Additives such as growth factors or bioactive agents may be added to the osteoinductive demineralized bone matrix. The osteoinductive demineralized bone matrix may form an osteogenic osteoimplant. The osteoimplant, when implanted in a mammalian body, may induce at the locus of the implant the full developmental cascade of endochondral bone formation including vascularization, mineralization, and bone marrow differentiation. The osteoinductive demineralized bone matrix may also be used as a delivery device to administer bioactive agents.


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