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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9415103 B1

PDFFull Text
Expired
Date of Patent:
Aug. 16, 2016

Filed:

Jun. 14, 2012

Combination therapy to prevent dcis formation and progression to breast cancer

Applicants:

Yosef Yarden, Rehovot, IL;

Pradeep Chaluvally-raghavan, Rehovot, IL;

Inventors:

Yosef Yarden, Rehovot, IL;

Pradeep Chaluvally-Raghavan, Rehovot, IL;

Assignee:

Yeda Research and Development Co. Ltd., Rehovot, IL;

Attorney:
Primary Examiner:

Bridget E Bunner

Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/713 (2006.01); A61K 31/7088 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C12Q 1/68 (2006.01); G01N 33/574 (2006.01); C12N 15/113 (2010.01); C07K 16/32 (2006.01); A61K 31/517 (2006.01); C07K 16/22 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); C07K 16/32 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57415 (2013.01); C12N 15/113 (2013.01); C12N 15/1135 (2013.01); C12N 15/1138 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01);
Abstract

A method of treating a ductal carcinoma in situ (DCIS) lesion in a subject in need thereof is disclosed. The method comprises administering to the subject a therapeutically effective amount of a first agent capable of down-regulating activity and/or expression of at least one component participating in a NOTCH pathway, and a second agent capable of down-regulating an activity and/or expression of HER2, thereby treating the DCIS lesion.

Find Patent Forward Citations

Yarden, Yosef. (2016). Combination therapy to prevent dcis formation and progression to breast cancer (U.S. Patent No. 9415103). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9415103

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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