The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2016

Filed:

Mar. 14, 2008
Applicants:

Rutledge Ellis-behnke, Canton, MA (US);

Terrence W. Norchi, Natick, MA (US);

Stephen Richard Kelly, Manchester, MA (US);

Inventors:

Rutledge Ellis-Behnke, Canton, MA (US);

Terrence W. Norchi, Natick, MA (US);

Stephen Richard Kelly, Manchester, MA (US);

Assignee:

Arch Biosurgery, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); A61K 38/07 (2006.01); A61K 38/08 (2006.01); C07K 5/103 (2006.01); C07K 7/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/07 (2013.01); A61K 38/08 (2013.01); A61K 38/10 (2013.01); C07K 5/1008 (2013.01); C07K 7/06 (2013.01);
Abstract

Self assembling peptides and peptidomimetics can be utilized for the treatment and support of disorders associated with leaky or damaged tight junction and weak, diseased, or injured extracellular matrix. The self-assembling materials generally have alternating hydrophilic or hydrophobic residues or hydrophobic and/or hydrophilic sections which allow the material to react or interact with the glycoproteins found in the ECM. Diseases in which treatment with these materials applied to or near the site in need of treatment include diabetic retinopathy, sepsis, burns, and certain neurodegenerative diseases such as Parkinson's and Alzheimer's. The formulations can be administered by injection, spraying, topically or by catheter or via a wound dressing or other material to which it is applied and then applied to the site in need of treatment.


Find Patent Forward Citations

Loading…