The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2016

Filed:

Aug. 31, 2010
Applicants:

Yasuki Kato, Kashiwa, JP;

Atsushi Ishii, Kashiwa, JP;

Inventors:

Yasuki Kato, Kashiwa, JP;

Atsushi Ishii, Kashiwa, JP;

Assignee:

Nanocarrier Co., Ltd., Kashiwa, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61K 31/7088 (2006.01); A61K 9/107 (2006.01); A61K 9/127 (2006.01); A61K 31/715 (2006.01); A61K 38/38 (2006.01); C12N 15/88 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7088 (2013.01); A61K 9/107 (2013.01); A61K 9/1271 (2013.01); A61K 9/1272 (2013.01); A61K 31/715 (2013.01); A61K 38/38 (2013.01); C12N 15/88 (2013.01);
Abstract

The present invention provides a particulate composition containing: block copolymer units being arranged radially with hydrophobic polymer-chain segments radially inside and hydrophilic polymer-chain segments radially outside; and a charged lipid which carries a charge opposite to the charge of a drug to be encapsulated, the charged lipid being attracted to the hydrophobic polymer-chain segment. In this particulate composition, the drug is retained within the particle via electrostatic binding with the charged lipid, whereby the outer surface of the particle is prevented from being charged to attract a substance which has a charge opposite to that of the charged lipid.


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