The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2016
Filed:
Mar. 14, 2014
Applicant:
Aerie Pharmaceuticals, Inc., Research Triangle Park, NC (US);
Inventors:
Casey Kopczynski, Chapel Hill, NC (US);
Cheng-Wen Lin, Raleigh, NC (US);
Jill Marie Sturdivant, Chapel Hill, NC (US);
Mitchell A. deLong, Chapel Hill, NC (US);
Assignee:
Aerie Pharmaceuticals, Inc., Research Triangle Park, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/22 (2006.01); A61K 31/4725 (2006.01); A61K 31/472 (2006.01); C07D 409/12 (2006.01); A61K 31/557 (2006.01); A61K 31/5575 (2006.01); A61K 31/559 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4725 (2013.01); A61K 31/472 (2013.01); A61K 31/557 (2013.01); A61K 31/559 (2013.01); A61K 31/5575 (2013.01); C07D 217/22 (2013.01); C07D 409/12 (2013.01);
Abstract
Described herein are compounds and compositions for treating glaucoma and/or reducing intraocular pressure. Compositions may comprise an isoquinoline compound and a prostaglandin or a prostaglandin analog. Compounds described herein include those in which an isoquinoline compound is covalently linked to a prostaglandin or a prostaglandin analog, and those in which an isoquinoline compound and a prostaglandin free acid together form a salt.