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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9410967 B1

PDFFull Text
Date of Patent:
Aug. 09, 2016

Filed:

May. 30, 2013

Methods and materials for monitoring myeloma using quantitative mass spectrometry

Applicant:

H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);

Inventors:

John Matthew Koomen, Tampa, FL (US);

Elizabeth Renee Remily, Lutz, FL (US);

Kaaron Benson, Apollo Beach, FL (US);

Mohamad Hussein, Odessa, FL (US);

Assignee:

H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);

Attorney:

Meunier Carlin & Curfman LLC

Primary Examiner:

James H Alstrum Acevedo

Assistant Examiner:

Tara Martinez

Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07K 16/06 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6857 (2013.01); C07K 16/065 (2013.01);
Abstract

The subject invention concerns methods and materials for diagnosing, monitoring the progress, and/or providing a prognosis for multiple myeloma and other conditions associated with antibody production in a person or animal. The methods of the invention utilize mass spectrometry for quantitative monitoring and detection of antibody produced by the plasma cells. The methods of the invention can be utilized for diagnosis, monitoring, and/or prognosis of multiple myeloma, monoclonal gammopathy, and other immunological or hematological conditions and disorders. In addition to detecting and quantifying antibody in a sample, other biological markers, such as serum albumin and/or beta-2-microglobulin, can also be detected and quantified using the present invention, and in combination with detection and quantification of antibody. Thus, in one embodiment, both antibody and serum albumin and/or beta-2-microglobulin are detected and quantified using mass spectrometry and a diagnosis or prognosis made based on the results and levels detected.

Find Patent Forward Citations

Koomen, John. (2016). Methods and materials for monitoring myeloma using quantitative mass spectrometry (U.S. Patent No. 9410967). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9410967

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