The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2016

Filed:

May. 14, 2013
Applicant:

The Cleveland Clinic Foundation, Cleveland, OH (US);

Inventors:

Suzy Comhair, Concord Township, OH (US);

Satish Kalhan, Pepper Pike, OH (US);

Stanley Hazen, Pepper Pike, OH (US);

Assignee:

THE CLEVELAND CLINIC FOUNDATION, Cleveland, OH (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/145 (2006.01); A61K 31/40 (2006.01); A61K 31/395 (2006.01); A61K 47/18 (2006.01); G01N 33/483 (2006.01); G01N 33/49 (2006.01); G01N 33/493 (2006.01);
U.S. Cl.
CPC ...
G01N 33/483 (2013.01); A61B 5/145 (2013.01); A61B 5/14546 (2013.01); A61K 31/395 (2013.01); A61K 31/40 (2013.01); A61K 47/183 (2013.01); G01N 33/49 (2013.01); G01N 33/493 (2013.01);
Abstract

The present invention provides methods, kits, and compositions related to testing a sample for the level of a biomarker related to asthma, wherein the biomarker is selected from: taurine, maltose, maltotriose, adenosine 5'-monophosphate, phosphoethanolamine, glycerophosphorylcholine, arachidonate, heptanoate, pelargonate, and nicotinamide. In certain embodiments, the level of the biomarker is used to identify therapy effective for treating asthma. In other embodiments, the level of the biomarker is used to identify the presence, severity, or risk of exacerbation of asthma. In further embodiments, the level of the biomarker is used to monitor the response to on-going therapy (e.g., adjust the dosage of the asthma therapy).


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