The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2016
Filed:
Dec. 18, 2012
Gaelle Saintigny, Paris, FR;
Christian Mahe, Neuilly sur Seine, FR;
Lionel Larue, Bures sur Yvette, FR;
Florian Rambow, Antony, FR;
Gaelle Saintigny, Paris, FR;
Christian Mahe, Neuilly sur Seine, FR;
Lionel Larue, Bures sur Yvette, FR;
Florian Rambow, Antony, FR;
CHANEL PARFUMS BEAUTE, Neuilly sur Seine, FR;
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, Paris, FR;
INSTITUT CURIE, Paris, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, Paris, FR;
Abstract
At least one microRNA selected from among hsa-miR-330, hsa-miR-7 and hsa-miR-137, the mature forms thereof, and the precursors thereof, for depigmenting the skin, and an in vitro method for identifying depigmenting compounds, which includes the steps of: a) placing at least one test compound in contact with a sample of melanocytes; b) measuring the expression or activity of at least one microRNA selected from among miR-330, miR-7 and miR-137, the mature forms thereof, and the precursors thereof, in the melanocytes; c) selecting the compounds for which at least 20% activation of the expression or of the activity of at least one of the microRNAs is measured in the melanocytes treated in a) by an element for comparing with the untreated melanocytes.