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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9410148 B1

PDFFull Text
Date of Patent:
Aug. 09, 2016

Filed:

Sep. 08, 2011

Method for constructing libraries of non-standard peptide compounds comprising n-methyl amino acids and other special (non-standard) amino acids and method for searching and identifying active species

Applicants:

Hiroaki Suga, Tokyo, JP;

Yusuke Yamagishi, Tokyo, JP;

Inventors:

Hiroaki Suga, Tokyo, JP;

Yusuke Yamagishi, Tokyo, JP;

Assignee:

THE UNIVERSITY OF TOKYO, Tokyo, JP;

Attorney:

Birch, Stewart, Kolasch & Birch, LLP

Primary Examiner:

Jeremy C Flinders

Int. Cl.
CPC ...
C12N 15/10 (2006.01); C40B 40/10 (2006.01); C40B 30/04 (2006.01); C40B 50/06 (2006.01); C07K 2/00 (2006.01); C12P 21/02 (2006.01); C40B 20/04 (2006.01); C12N 15/67 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1062 (2013.01); C07K 2/00 (2013.01); C12P 21/02 (2013.01); C40B 30/04 (2013.01); C40B 40/10 (2013.01); C40B 50/06 (2013.01); C12N 15/67 (2013.01); C40B 20/04 (2013.01); G01N 2500/00 (2013.01); G01N 2500/20 (2013.01);
Abstract

A method for screening a non-standard peptide compound in the peptide library that binds to the target substance, comprising the steps: (i) preparing a non-standard peptide library wherein a special (non-standard) amino acid is randomly incorporated into the peptide sequence by a cell-free (in vitro) translation system comprising a tRNA acylated by a special (non-standard) amino acid; (ii) bringing the obtained peptide library in contact with a target substance; and (iii) selecting a non-standard peptide that binds to the target substance as an active peptide.

Find Patent Forward Citations

Suga, Hiroaki. (2016). Method for constructing libraries of non-standard peptide compounds comprising n-methyl amino acids and other special (non-standard) amino acids and method for searching and identifying active species (U.S. Patent No. 9410148). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9410148

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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