The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2016
Filed:
Jul. 02, 2015
Applicant:
Acorda Therapeutics, Inc., Ardsley, NY (US);
Inventors:
Anthony O. Caggiano, Larchmont, NY (US);
Andrea Vecchione, Mt. Vernon, NY (US);
Jennifer Iaci, Boonton, NJ (US);
Assignee:
Acorda Therapeutics, Inc., Ardsley, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/64 (2006.01); C12P 19/34 (2006.01); C12P 21/06 (2006.01); C12N 15/00 (2006.01); C12N 9/88 (2006.01); C12N 9/26 (2006.01); C12N 9/24 (2006.01); C12N 9/14 (2006.01); C07H 21/04 (2006.01); C07K 1/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/88 (2013.01); C12Y 402/02021 (2013.01); A61K 38/00 (2013.01); C12Y 402/0202 (2013.01);
Abstract
The present disclosure relates to protein and nucleic acid mutants of chondroitinase ABCI. Such nucleic acid mutants encode for chondroitinase ABCI mutant enzymes exhibiting altered chondroitin lyase activity or increased resistance to inactivation from stressors including UV light or heat. Methods of using such nucleic acid mutants encoding chondroitinase ABCI mutant enzymes is also provided.