The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2016
Filed:
Sep. 12, 2008
Gilles Dadaglio, Chatillen, FR;
Claude Leclerc, Paris, FR;
Daniel Ladant, Cachan, FR;
Benoît Van Den Eynde, Brussels, BE;
Sandra Morel, Brussels, BE;
Cécile Bauche, Paris, FR;
Gilles Dadaglio, Chatillen, FR;
Claude Leclerc, Paris, FR;
Daniel Ladant, Cachan, FR;
Benoît Van Den Eynde, Brussels, BE;
Sandra Morel, Brussels, BE;
Cécile Bauche, Paris, FR;
INSTITUT PASTEUR, Paris, FR;
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), Paris, FR;
LUDWIG INSTITUT FOR CANCER RESEARCH, New York, NY (US);
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris, FR;
Abstract
An immunogenic composition comprising a recombinant protein comprising aCyaA, or a fragment thereof, and a peptide that corresponds to a tumor antigen is provided as a cancer treatment. Methods of treatment with this immunogenic composition are also provided. In an embodiment, the therapeutic composition is a treatment for melanoma, and comprises epitopes from the HLA*0201 epitope. These epitopes include Tyr or GnT-V, and are present in the recombinant proteins CyaA-E5-Tyr and CyaA-E5-GnT-V.