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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9409964 B1

PDFFull Text
Expired
Date of Patent:
Aug. 09, 2016

Filed:

Apr. 29, 2014

Rationally designed antibodies

Applicant:

Alexion Pharmaceuticals, Inc., Cheshire, CT (US);

Inventors:

Katherine S. Bowdish, Del Mar, CA (US);

Shana Frederickson, Solana Beach, CA (US);

Mark Renshaw, San Diego, CA (US);

Assignee:

Alexion Pharmaceuticals, Inc., New Haven, CT (US);

Attorneys:

Nelson Mullins Riley & Scarborough LLP

Jane E. Remillard, Esq.

Christopher L. Frank

Primary Examiner:

Yan Xiao

Int. Cl.
CPC ...
A61K 35/14 (2015.01); C07K 16/00 (2006.01); C07K 7/00 (2006.01); C07K 14/505 (2006.01); C07K 14/52 (2006.01); C07K 16/12 (2006.01); C07K 16/18 (2006.01); C07K 16/46 (2006.01); C12N 5/078 (2010.01); A61K 39/00 (2006.01); A61K 39/40 (2006.01);
U.S. Cl.
CPC ...
C07K 14/505 (2013.01); C07K 14/524 (2013.01); C07K 16/00 (2013.01); C07K 16/005 (2013.01); C07K 16/1282 (2013.01); C07K 16/18 (2013.01); C07K 16/46 (2013.01); C12N 5/0641 (2013.01); A61K 39/00 (2013.01); A61K 39/40 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/74 (2013.01); C07K 2318/10 (2013.01); C07K 2319/00 (2013.01); C07K 2319/036 (2013.01); C07K 2319/30 (2013.01); C07K 2319/75 (2013.01); C12N 2501/14 (2013.01); C12N 2506/11 (2013.01);
Abstract

Antibodies or fragments thereof having CDR regions replaced or fused with biologically active peptides are described. Flanking sequences may optionally be attached at one or both the carboxy-terminal and amino-terminal ends of the peptide in covalent association with adjacent framework regions. Compositions containing such antibodies or fragments thereof are useful in therapeutic and diagnostic modalities.

Find Patent Forward Citations

Bowdish, Katherine. (2016). Rationally designed antibodies (U.S. Patent No. 9409964). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9409964

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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