The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2016
Filed:
Jul. 08, 2013
Applicant:
Korea Institute of Science and Technology, Seoul, KR;
Inventors:
Kwang Meyung Kim, Seoul, KR;
Ick Chan Kwon, Seoul, KR;
Sang Yoon Kim, Seoul, KR;
Ju Hee Ryu, Seoul, KR;
Eun Sung Jun, Daegu, KR;
In San Kim, Daegu, KR;
Assignee:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, Seoul, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 499/78 (2006.01); C07D 209/62 (2006.01); C07D 409/14 (2006.01); C07D 498/08 (2006.01);
U.S. Cl.
CPC ...
C07D 499/78 (2013.01); C07D 209/62 (2013.01); C07D 409/14 (2013.01); C07D 498/08 (2013.01);
Abstract
Disclosed is a drug-fluorophore complex for specific detection of tumor cells. Specifically, the drug-fluorophore complex includes a tumor cell-targeting drug penetrating tumor cells and non-tumor cells at different rates or levels, and a fluorescent substance chemically bonded to the tumor cell-targeting drug. The drug-fluorophore complex enables specific imaging of tumor cells only with high accuracy in a very simple manner without causing cytotoxicity.