The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2016
Filed:
Oct. 29, 2014
Applicant:
Taivex Therapeutics Corporation, Taipei, TW;
Inventors:
Johnson Lau, Newport Beach, CA (US);
Jiann-Jyh Huang, Yilan County, TW;
Assignee:
Taivex Therapeutics Corporation, Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4436 (2006.01); C07D 417/14 (2006.01); A61K 31/427 (2006.01); A61K 31/4439 (2006.01); A61K 31/496 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); C07D 417/12 (2006.01); A61K 31/426 (2006.01); A61K 31/444 (2006.01); A61K 31/4545 (2006.01); C07D 277/44 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); A61K 31/426 (2013.01); A61K 31/427 (2013.01); A61K 31/444 (2013.01); A61K 31/4439 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); C07D 277/44 (2013.01); C07D 417/12 (2013.01);
Abstract
Compounds, compositions, and methods for modulation of Hec1/Nek2 interaction are provided. Especially preferred compounds disrupt Nek2/Hec1 binding and are therefore useful as chemotherapeutic agent for neoplastic diseases.