The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2016

Filed:

Nov. 21, 2013
Applicants:

Array Biopharma Inc., Boulder, CO (US);

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Josef Bencsik, Boulder, CO (US);

James F. Blake, Boulder, CO (US);

James M. Graham, Boulder, CO (US);

Martin F. Hentemann, Boulder, CO (US);

Nicholas C. Kallan, Boulder, CO (US);

Ian S. Mitchell, Boulder, CO (US);

Stephen T. Schlachter, Boulder, CO (US);

Keith L. Spencer, Boulder, CO (US);

Dengming Xiao, Boulder, CO (US);

Rui Xu, Boulder, CO (US);

Mike Welch, Boulder, CO (US);

Jun Liang, South San Francisco, CA (US);

Brian S. Safina, South San Francisco, CA (US);

Assignees:

ARRAY BIOPHARMA INC., Boulder, CO (US);

GENENTECH, INC., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); C07D 401/12 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/12 (2006.01); C07D 403/14 (2006.01); A61P 35/02 (2006.01); A61P 35/04 (2006.01); A61P 29/00 (2006.01); A61P 9/00 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); A61P 25/16 (2006.01); A61P 31/04 (2006.01); A61P 37/06 (2006.01); A61P 37/08 (2006.01); A61P 17/06 (2006.01); A61P 11/06 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); C07D 401/12 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/12 (2013.01);
Abstract

The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.


Find Patent Forward Citations

Loading…