The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2016

Filed:

Mar. 25, 2011
Applicants:

Bernard Bunner, Newton, MA (US);

Theodore A. Dourdeville, Providence, RI (US);

Inventors:

Bernard Bunner, Newton, MA (US);

Theodore A. Dourdeville, Providence, RI (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B23K 20/02 (2006.01); B01L 3/00 (2006.01); B23K 20/233 (2006.01); G01N 30/60 (2006.01); H01J 49/00 (2006.01); H01J 49/16 (2006.01); B23K 101/18 (2006.01); B23K 103/14 (2006.01); G01N 30/72 (2006.01);
U.S. Cl.
CPC ...
B23K 20/023 (2013.01); B01L 3/502707 (2013.01); B01L 3/502753 (2013.01); B23K 20/233 (2013.01); G01N 30/6095 (2013.01); H01J 49/0018 (2013.01); H01J 49/167 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0887 (2013.01); B01L 2400/0487 (2013.01); B23K 2201/18 (2013.01); B23K 2203/14 (2013.01); G01N 30/7266 (2013.01);
Abstract

A microfluidic device for separating a sample by chromatography includes diffusion bonded metallic sheets joined together to create a hermetically sealed interface between each adjacent metallic sheet without the introduction of a secondary material. Enclosed within the diffusion bonded sheets is a separation channel accessible by at least one of an inlet or an outlet. The separation channel is packed with micrometer-sized particles serving as a stationary phase in a chromatographic separation. Wetted surfaces of the separation channel include a coating of an organic material at least one monolayer thick.


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