The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2016

Filed:

Jan. 30, 2012
Applicants:

Amlanjyoti Dhar, Kolkata, IN;

Shampa Mallick, Kolkata, IN;

Israr Ahmed, Kolkata, IN;

Aditya Konar, Kolkata, IN;

Santu Bandyopadhyay, Kolkata, IN;

Siddhartha Roy, Kolkata, IN;

Inventors:

Amlanjyoti Dhar, Kolkata, IN;

Shampa Mallick, Kolkata, IN;

Israr Ahmed, Kolkata, IN;

Aditya Konar, Kolkata, IN;

Santu Bandyopadhyay, Kolkata, IN;

Siddhartha Roy, Kolkata, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61K 38/10 (2006.01); A61K 9/00 (2006.01); C07K 14/47 (2006.01); A61K 45/06 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/16 (2013.01); A61K 9/0019 (2013.01); A61K 38/10 (2013.01); A61K 45/06 (2013.01); C07K 14/00 (2013.01); C07K 14/47 (2013.01);
Abstract

The present invention describes a novel bivalent helically constrained peptide targeted against S100B that is an effective anti-cancer drug against cancers that over-express S100B. This helix mimetic targeted against S100B induces rapid apoptosis in cancer cells that over-express a calcium binding protein S100B through simultaneous inhibition of key growth pathways including activation of p53.


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