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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9408850 B1

PDFFull Text
Date of Patent:
Aug. 09, 2016

Filed:

May. 07, 2012

Substituted indazole derivatives active as kinase inhibitors

Applicants:

Andrea Lombardi Borgia, Paullo, IT;

Marina Ciomei, Corsico, IT;

Daniele Donati, Nerviano, IT;

Marcella Nesi, Saronno, IT;

Inventors:

Andrea Lombardi Borgia, Paullo, IT;

Marina Ciomei, Corsico, IT;

Daniele Donati, Nerviano, IT;

Marcella Nesi, Saronno, IT;

Assignee:

NERVIANO MEDICAL SCIENCES S.R.L., Nerviano (MI), IT;

Attorney:

Scully, Scott, Murphy & Presser, P.C.

Primary Examiner:

Kamal Saeed

Int. Cl.
CPC ...
C07D 231/56 (2006.01); C07D 401/12 (2006.01); C07D 295/185 (2006.01); C07D 405/12 (2006.01); C07D 403/12 (2006.01); A61K 31/496 (2006.01); A61K 31/416 (2006.01); A61K 31/5377 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); A61K 31/454 (2006.01); A61K 45/06 (2006.01); C07D 295/155 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/416 (2013.01); A61K 31/454 (2013.01); A61K 31/496 (2013.01); A61K 45/06 (2013.01); C07D 231/56 (2013.01); C07D 295/155 (2013.01); C07D 295/185 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01);
Abstract

The present invention relates to substituted indazole compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by degulated protein kinase activity, like cancer. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such these compounds or the pharmaceutical compositions containing them.

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