The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2016

Filed:

Dec. 05, 2014
Applicant:

The Translational Genomics Research Institute, Phoenix, AZ (US);

Inventors:

Timothy G. Whitsett, Phoenix, AZ (US);

Nhan L. Tran, Phoenix, AZ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 48/00 (2006.01); G01N 33/574 (2006.01); C12Q 1/68 (2006.01); A61K 31/713 (2006.01); A61K 45/06 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
G01N 33/57423 (2013.01); A61K 31/713 (2013.01); A61K 45/06 (2013.01); C12N 15/1138 (2013.01); C12Q 1/6886 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2320/30 (2013.01); C12Q 2600/158 (2013.01);
Abstract

Embodiments of the invention provide a method detecting and treating cancer, such as lung cancer. In some aspects, the method may include detecting cancer in a subject, which may comprise assessing the expression of a marker in a sample from the subject. For example, the marker may comprise c-Met and/or Fn14. In some embodiments, if the subject is diagnosed as having cancer, the method may further provide administering a therapeutically effective amount of a substance that reduces the expression level of Fn14 to the subject to reduce the invasive and migratory capabilities of the cancer.


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