The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2016

Filed:

Feb. 10, 2014
Applicant:

Somalogic, Inc., Boulder, CO (US);

Inventors:

Daniel J. Schneider, Arvada, CO (US);

Dan Nieuwlandt, Longmont, CO (US);

Bruce Eaton, Longmont, CO (US);

Martin Stanton, Boulder, CO (US);

Shashi Gupta, Louisville, CO (US);

Stephan Kraemer, Boulder, CO (US);

Dominic Zichi, Boulder, CO (US);

Larry Gold, Boulder, CO (US);

Assignee:

SOMALOGIC, INC., Boulder, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/543 (2006.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5308 (2013.01); G01N 33/54306 (2013.01); G01N 33/6863 (2013.01); G01N 33/74 (2013.01);
Abstract

The present disclosure describes methods, devices, reagents, and kits for the detection of one or more target molecules that may be present in a test sample. The described methods, devices, kits, and reagents facilitate the detection and quantification of a non-nucleic acid target (e.g., a protein target) in a test sample by detecting and quantifying a nucleic acid (i.e., an aptamer). The methods described create a nucleic acid surrogate for a non-nucleic acid target, thus allowing the wide variety of nucleic acid technologies, including amplification, to be applied to a broader range of desired targets, especially protein targets. The disclosure further describes aptamer constructs that facilitate the use of aptamers in a variety of analytical detection applications.


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