The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2016
Filed:
Mar. 02, 2012
Maxime Dahan, Paris, FR;
Mathieu Morel, Paris, FR;
Jean-christophe Galas, Paris, FR;
Vincent Studer, Bordeaux, FR;
Denis Bartolo, Paris, FR;
Maxime Dahan, Paris, FR;
Mathieu Morel, Paris, FR;
Jean-Christophe Galas, Paris, FR;
Vincent Studer, Bordeaux, FR;
Denis Bartolo, Paris, FR;
Centre National de la Recherche Scientifique-CNRS, Paris, FR;
Ecole Normale Supérieure, Paris, FR;
Université Pierre et Marie Curie (Paris 6), Paris, FR;
Fonds De L'ESPCI-Georges Charpak, Paris, FR;
Univerité Bordeaux Segalen, Bordeaux, FR;
Abstract
The invention relates to a microfluidic system for controlling a concentration profile of molecules capable of stimulating a target, for example formed by an assembly of living cells, this system comprising: —a microfluidic device () comprising at least one microfluidic channel () equipped with at least one inlet orifice () and with at least one outlet orifice () for at least one fluid; —at least one means for supplying the microfluidic channel () with at least one fluid comprising molecules capable of stimulating the target; —at least one chamber () or another microfluidic channel comprising a base () intended to receive the target; and —at least one microporous membrane () separating the chamber () or the other microfluidic channel from the microfluidic channel (), said microporous membrane () being positioned away from the base () so that when the supply means provides the microfludic channel () with said at least one fluid flowing in laminar flow in contact with the microporous membrane (), the molecules capable of stimulating the target then diffuse, after having passed through the microporous membrane () through the chamber () or said other microfluidic channel in order to finally form a stable concentration profile in this chamber () or this other microfluidic channel.