The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2016

Filed:

Dec. 21, 2012
Applicants:

Joseph Herman, West Chester, PA (US);

Sarah J. Fair, Manchaug, MA (US);

Dayana Argoti, Charlestown, MA (US);

Inventors:

Joseph Herman, West Chester, PA (US);

Sarah J. Fair, Manchaug, MA (US);

Dayana Argoti, Charlestown, MA (US);

Assignee:

Thermo Finnigan LLC, San Jose, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 30/02 (2006.01); G01N 30/08 (2006.01); G01N 30/14 (2006.01); G01N 30/46 (2006.01);
U.S. Cl.
CPC ...
G01N 30/02 (2013.01); G01N 30/08 (2013.01); G01N 30/14 (2013.01); G01N 30/462 (2013.01); G01N 30/468 (2013.01); G01N 2030/143 (2013.01);
Abstract

An apparatus comprises: a first chromatographic column fluidically coupled to a source of sample and a source of a first chromatographic mobile phase solvent; a second chromatographic column fluidically coupled to the first column; a source of a second mobile phase solvent fluidically coupled between the first and second columns; and a detector, the first chromatographic column being configurable to receive, in a trapping step, the first solvent and sample and to retain a first portion of a plurality of analytes therein and to pass a second portion of the plurality of analytes therethrough, the second chromatographic column being configurable, in the trapping step, to receive the second portion of the plurality of analytes and the first and second solvents and to retain the second portion of the plurality of analytes therein, the detector being arranged to receive the second and first portions in respective first and second elution steps.


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