The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2016
Filed:
Jul. 14, 2015
Applicants:
Pierfrancesco Tassone, Catanzaro, IT;
Pierosandro Tagliaferri, Naples, IT;
Maria Teresa Di Martino, Catanzaro, IT;
Inventors:
Pierfrancesco Tassone, Catanzaro, IT;
Pierosandro Tagliaferri, Naples, IT;
Maria Teresa Di Martino, Catanzaro, IT;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 48/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); C12N 15/113 (2013.01); C12N 2310/113 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/3231 (2013.01); C12N 2310/346 (2013.01);
Abstract
Inhibitors of miRNAs 221 and 222, and their use as medicaments in the treatment of multiple myeloma. The inhibitors inhibit miRNAs 221 and 222 of the type of LNA-miRNAs and have the formula +C*A*G*+A*+C*A*+A*T*+G*T*+A*+G*C, and formula C*+A*+G*+A*T*+G*T*+A*+G*C wherein letters with symbol '+' indicate the positions of LNA and symbol '*' indicates phosphorothioate bonds.