The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2016
Filed:
Sep. 16, 2015
Applicant:
Ovascience, Inc., Cambridge, MA (US);
Inventors:
David T. Weaver, Newton, MA (US);
Bo Zhang, Lynnfield, MA (US);
Assignee:
OvaScience, Inc., Waltham, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); G01N 33/56966 (2013.01); C07K 2317/21 (2013.01); C07K 2317/565 (2013.01);
Abstract
Anti-VASA antibodies (mAbs), particularly humanized mAbs that specifically bind to VASA with high affinity, are disclosed. The amino acid sequences of the CDRs of the light chains and the heavy chains, as well as consensus sequences for these CDRs, of these anti-VASA mAbs are provided. The disclosure also provides nucleic acid molecules encoding the anti-VASA mAbs, expression vectors, host cells, methods for making the anti-VASA mAbs, and methods for expressing the anti-VASA mAbs. Finally, methods of using the anti-VASA mAbs to isolate and/or purify cells expressing VASA are disclosed.