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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9403869 B1

PDFFull Text
Expired
Date of Patent:
Aug. 02, 2016

Filed:

Mar. 30, 2007

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Applicants:

Bharat Kumar Majeti, La Jolla, CA (US);

Priya Prakash Karmali, La Jolla, CA (US);

Pramanik Dipankar, Andhra Pradesh, IN;

Arabinda Chaudhuri, Andhra Pradesh, IN;

Inventors:

Bharat Kumar Majeti, La Jolla, CA (US);

Priya Prakash Karmali, La Jolla, CA (US);

Pramanik Dipankar, Andhra Pradesh, IN;

Arabinda Chaudhuri, Andhra Pradesh, IN;

Assignee:

Council of Scientific and Industrial Research, New Delhi, IN;

Attorney:

Harness, Dickey & Pierce, PLC

Primary Examiner:

Suzanne Ziska

Assistant Examiner:

Thurman Wheeler

Int. Cl.
CPC ...
A61K 38/16 (2006.01); C07K 5/11 (2006.01); A61K 31/711 (2006.01); A61K 31/7105 (2006.01); A61P 35/00 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/1019 (2013.01); A61K 48/0008 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01);
Abstract

The present invention provides synthesis of a novel series of cationic lipopeptides with integrin-binding RGD functionalities. The invention also provides high L27 (transformed S1 80, mouse sarcoma cells) cell tropic gene transfer properties of these novel RGD-lipopeptides. Since L27 cell surface contains over expressed integrins, the present class of lipopeptides with integrin-binding RGD ligands are likely to find future applications in targeting anti-cancer genes/drugs to the endothelial cells of tumor vasculatures (possessing over expressed integrins).

Find Patent Forward Citations

Majeti, Bharat. (2016). [object object] (U.S. Patent No. 9403869). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9403869

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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