The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2016
Filed:
Aug. 03, 2015
Applicant:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Inventors:
Shaomeng Wang, Saline, MI (US);
Jianfang Chen, Ann Arvor, MI (US);
Donna McEachern, Ann Arbor, MI (US);
Longchuan Bai, Ann Arbor, MI (US);
Liu Liu, Ann Arbor, MI (US);
Duxin Sun, Ann Arbor, MI (US);
Xiaoqin Li, Ann Arbor, MI (US);
Angelo Aguilar, Ann Arbor, MI (US);
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07F 9/6558 (2006.01); A61K 31/496 (2006.01); A61K 31/675 (2006.01); A61K 45/06 (2006.01); A61N 5/10 (2006.01); A61K 33/30 (2006.01);
U.S. Cl.
CPC ...
C07F 9/65583 (2013.01); A61K 31/675 (2013.01); A61K 33/30 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01);
Abstract
Inhibitors of Bcl-2/Bcl-xL and compositions containing the same are disclosed. Methods of using the Bcl-2/Bcl-xL inhibitors in the treatment of diseases and conditions wherein inhibition of Bcl-2/Bcl-xL provides a benefit, like cancers, also are disclosed.