The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2016
Filed:
Sep. 11, 2014
Applicant:
Lexicon Pharmaceuticals, Inc., The Woodlands, TX (US);
Inventors:
Yingzhi Bi, Plainsboro, NJ (US);
Kenneth Gordon Carson, Princeton, NJ (US);
Giovanni Cianchetta, Waltham, MA (US);
Michael Alan Green, Easton, PA (US);
Godwin Kumi, Rocky Hill, CT (US);
Alan Main, Far Hills, NJ (US);
Yulian Zhang, Action, MA (US);
Glenn Gregory Zipp, Robbinsville, NJ (US);
Assignee:
Lexicon Pharmaceuticals, Inc., The Woodlands, TX (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/519 (2013.01); C07B 59/002 (2013.01); C07B 2200/05 (2013.01);
Abstract
Pyrazolo[1,5-a]pyrimidine-based compounds of the formula: are disclosed, wherein R, Rand Rare defined herein. Compositions comprising the compounds and methods of their use to treat, manage and/or prevent diseases and disorders mediated by adaptor associated kinase 1 activity are also disclosed.