The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2016

Filed:

Jul. 16, 2013
Applicants:

Asitha Abeywardane, Danbury, CT (US);

Steven Richard Brunette, New Milford, CT (US);

Michael Jason Burke, Newtown, CT (US);

Thomas Martin Kirrane, Jr., Middlebury, CT (US);

Chuk Chui Man, Ridgefield, CT (US);

Daniel Richard Marshall, Norwalk, CT (US);

Anil Kumar Padyana, Oxford, CT (US);

Hossein Razavi, Danbury, CT (US);

Robert Sibley, North Haven, CT (US);

Lana Louise Smith Keenan, Poughquag, NY (US);

Roger John Snow, Danbury, CT (US);

Ronald John Sorcek, Bethel, CT (US);

Hidenori Takahashi, LaGrangeville, NY (US);

Steven John Taylor, Southbury, CT (US);

Michael Robert Turner, Danbury, CT (US);

Erick Richard Roush Young, Danbury, CT (US);

Qiang Zhang, Woodbury, CT (US);

Yunlong Zhang, North Haven, CT (US);

Renee M. Zindell, New Milford, CT (US);

Inventors:

Asitha Abeywardane, Danbury, CT (US);

Steven Richard Brunette, New Milford, CT (US);

Michael Jason Burke, Newtown, CT (US);

Thomas Martin Kirrane, Jr., Middlebury, CT (US);

Chuk Chui Man, Ridgefield, CT (US);

Daniel Richard Marshall, Norwalk, CT (US);

Anil Kumar Padyana, Oxford, CT (US);

Hossein Razavi, Danbury, CT (US);

Robert Sibley, North Haven, CT (US);

Lana Louise Smith Keenan, Poughquag, NY (US);

Roger John Snow, Danbury, CT (US);

Ronald John Sorcek, Bethel, CT (US);

Hidenori Takahashi, LaGrangeville, NY (US);

Steven John Taylor, Southbury, CT (US);

Michael Robert Turner, Danbury, CT (US);

Erick Richard Roush Young, Danbury, CT (US);

Qiang Zhang, Woodbury, CT (US);

Yunlong Zhang, North Haven, CT (US);

Renee M. Zindell, New Milford, CT (US);

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 471/20 (2006.01); C07D 491/20 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61K 31/549 (2006.01); A61K 31/55 (2006.01); A61K 31/551 (2006.01); C07D 405/12 (2006.01); C07D 497/08 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/5377 (2013.01); A61K 31/549 (2013.01); A61K 31/55 (2013.01); A61K 31/551 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 471/20 (2013.01); C07D 491/20 (2013.01); C07D 497/08 (2013.01); C07D 498/04 (2013.01);
Abstract

The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein A, A, Land B are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene Ahydrolase (LTAH) and treating LTAH related disorders. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.


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