The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2016
Filed:
Jan. 31, 2012
Jutta Heim, Ramlinsburg, CH;
Peter Schneider, Bottmingen/BL, CH;
Patrick Roussel, Mulhouse, FR;
Daniel Milligan, San Francisco, CA (US);
Christian Bartels, Allschwil/BL, CH;
Glenn Dale, Basel, CH;
Jutta Heim, Ramlinsburg, CH;
Peter Schneider, Bottmingen/BL, CH;
Patrick Roussel, Mulhouse, FR;
Daniel Milligan, San Francisco, CA (US);
Christian Bartels, Allschwil/BL, CH;
Glenn Dale, Basel, CH;
Emergent Product Development Gaithersburg Inc., Gaithersburg, MD (US);
Abstract
This invention provides novel 4-oxoquinolizine compounds and their uses for a series of broad-spectrum antibiotics having no cross-resistance to existing or emerging classes of antibiotics. In addition the novel 4-oxoquinolizine compounds are useful against CDC Category A and B pathogens The invention also provides pharmaceutical compositions comprising certain 4-oxoquinolizines in combination with subinhibitory concentrations of polymyxin B against clinical isolates which are resistant to quinolones, carbapenems and other antimicrobial agents.