The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2016
Filed:
Mar. 31, 2014
Hong Kong Baptist University, Hong Kong, HK;
Lei Guo, Hong Kong, HK;
Di Xu, Hong Kong, HK;
See-Lok Ho, Hong Kong, HK;
Chung-Yan Poon, Hong Kong, HK;
Olivia T. W. Ng, Hong Kong, HK;
Hung Wing Li, Hong Kong, HK;
Ken K. L. Yung, Hong Kong, HK;
Daniel W. J. Kwong, Hong Kong, HK;
Ricky M. S. Wong, Hong Kong, HK;
HONG KONG BAPTIST UNIVERSITY, Kowloon Tong, Kowloon, HK;
Abstract
The present invention is in the field of pharmaceuticals and chemical industries. In particular, the present invention relates to methods for labeling, imaging and detecting the beta-amyloid (Aβ) peptides, oligomers, and fibrils in vitro by using carbazole-based fluorophores. A further aspect of the present invention relates to a method of reducing and preventing aggregation of beta-amyloid peptides for Alzheimer's disease (AD) as well as of treating and/or preventing Alzheimer's disease by using carbazole-based fluorophores.