The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2016
Filed:
Sep. 25, 2013
Applicant:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Inventors:
William F. DeGrado, San Francisco, CA (US);
Jun Wang, Philadelphia, PA (US);
Assignee:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 255/47 (2006.01); C07C 61/13 (2006.01); C07C 211/38 (2006.01); C07D 223/32 (2006.01); C07C 49/447 (2006.01); C07C 49/427 (2006.01); A61K 31/045 (2006.01); A61K 31/122 (2006.01); A61K 31/13 (2006.01); A61K 31/19 (2006.01); A61K 31/277 (2006.01); A61K 31/55 (2006.01); C07C 35/23 (2006.01); C07C 49/323 (2006.01); C07C 49/623 (2006.01); C07C 211/19 (2006.01);
U.S. Cl.
CPC ...
C07D 223/32 (2013.01); A61K 31/045 (2013.01); A61K 31/122 (2013.01); A61K 31/13 (2013.01); A61K 31/19 (2013.01); A61K 31/277 (2013.01); A61K 31/55 (2013.01); C07C 35/23 (2013.01); C07C 49/323 (2013.01); C07C 49/427 (2013.01); C07C 49/447 (2013.01); C07C 49/623 (2013.01); C07C 61/13 (2013.01); C07C 211/19 (2013.01); C07C 211/38 (2013.01); C07C 255/47 (2013.01); C07C 2102/50 (2013.01);
Abstract
Provided are compounds that are capable of modulating the activity of the influenza A virus via interaction with the M2 transmembrane protein. Also provided are methods for treating an influenza A-affected disease state or infection comprising administering a composition comprising one or more compounds that have been identified as being capable of interaction with the M2 protein.