The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2016

Filed:

Jun. 30, 2015
Applicant:

Neumodx Molecular, Inc., Ann Arbor, MI (US);

Inventors:

Jeffrey Williams, Chelsea, MI (US);

Michael T. Kusner, Ann Arbor, MI (US);

Assignee:

NeuMoDx Molecular, Inc., Ann Arbor, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12Q 1/68 (2006.01); F04B 43/02 (2006.01); B01L 7/00 (2006.01); C12M 3/00 (2006.01); C12N 13/00 (2006.01); B29C 65/08 (2006.01); B29C 65/60 (2006.01); B29C 65/00 (2006.01); B29L 31/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502 (2013.01); B01L 3/5027 (2013.01); B01L 3/502707 (2013.01); B01L 3/502738 (2013.01); B01L 7/52 (2013.01); B01L 7/525 (2013.01); C12M 23/42 (2013.01); C12Q 1/68 (2013.01); C12Q 1/686 (2013.01); B01L 3/5025 (2013.01); B01L 3/50273 (2013.01); B01L 3/502723 (2013.01); B01L 3/502746 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/10 (2013.01); B01L 2200/142 (2013.01); B01L 2300/021 (2013.01); B01L 2300/022 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0809 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0883 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/123 (2013.01); B01L 2300/14 (2013.01); B01L 2300/16 (2013.01); B01L 2300/1827 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0481 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0622 (2013.01); B01L 2400/0655 (2013.01); B01L 2400/0694 (2013.01); B01L 2400/086 (2013.01); B29C 65/08 (2013.01); B29C 65/606 (2013.01); B29C 66/71 (2013.01); B29C 66/81423 (2013.01); B29C 66/8322 (2013.01); B29L 2031/756 (2013.01); C12N 13/00 (2013.01);
Abstract

A microfluidic cartridge, configured to facilitate processing and detection of nucleic acids, comprising: a top layer comprising a set of cartridge-aligning indentations, a set of sample port-reagent port pairs, a shared fluid port, a vent region, a heating region, and a set of Detection chambers; an intermediate substrate, coupled to the top layer comprising a waste chamber; an elastomeric layer, partially situated on the intermediate substrate; and a set of fluidic pathways, each formed by at least a portion of the top layer and a portion of the elastomeric layer, wherein each fluidic pathway is fluidically coupled to a sample port-reagent port pair, the shared fluid port, and a Detection chamber, comprises a turnabout portion passing through the heating region, and is configured to be occluded upon deformation of the elastomeric layer, to transfer a waste fluid to the waste chamber, and to pass through the vent region.


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