The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2016

Filed:

Mar. 06, 2014
Applicant:

Allergan, Inc., Irvine, CA (US);

Inventors:

Santosh C. Sinha, Ladera Ranch, CA (US);

Ken Chow, Newport Coast, CA (US);

Liming Wang, Irvine, CA (US);

Michael E. Garst, Newport Beach, CA (US);

Mayssa Attar, Placentia, CA (US);

Brandon D. Swift, Camarillo, CA (US);

Assignee:

Allergan, Inc., Irvine, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01); C07K 7/64 (2006.01); A61K 47/48 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48115 (2013.01); A61K 9/0048 (2013.01); A61K 47/481 (2013.01); A61K 47/48123 (2013.01); A61K 47/48246 (2013.01); C07K 7/645 (2013.01);
Abstract

The present invention describes Cyclosporine A/steroid hybrid analogs. These single drug entities are formed by connecting a steroid with Cyclosporine A. Upon topical application to the eye, the conjugate hybrid would undergo enzymatic and/or hydrolytic cleavage to release the individual drugs.


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