The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2016
Filed:
Mar. 06, 2014
Applicant:
Allergan, Inc., Irvine, CA (US);
Inventors:
Santosh C. Sinha, Ladera Ranch, CA (US);
Ken Chow, Newport Coast, CA (US);
Liming Wang, Irvine, CA (US);
Michael E. Garst, Newport Beach, CA (US);
Mayssa Attar, Placentia, CA (US);
Brandon D. Swift, Camarillo, CA (US);
Assignee:
Allergan, Inc., Irvine, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/12 (2006.01); A61K 47/48 (2006.01); A61K 9/00 (2006.01); C07D 215/56 (2006.01); C07D 401/04 (2006.01); C07D 471/04 (2006.01); C07D 498/06 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48115 (2013.01); A61K 9/0048 (2013.01); A61K 47/48123 (2013.01); C07D 215/56 (2013.01); C07D 401/04 (2013.01); C07D 405/12 (2013.01); C07D 471/04 (2013.01); C07D 498/06 (2013.01);
Abstract
The present invention describes novel single drug entities, formed by direct linkage of an antibiotic to a steroidal drug. Upon topical application to the eye, the conjugate would undergo enzymatic and/or hydrolytic cleavage to release the individual drugs. The antibiotic is coupled directly to the steroid drug.