The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2016

Filed:

Jan. 10, 2014
Applicant:

Abbvie Deutschland Gmbh & Co. KG, Wiesbaden, DE;

Inventors:

Bernd Liepold, Dossenheim, DE;

Jörg Breitenbach, Mannheim, DE;

Markus Mägerlein, Mannheim, DE;

Claudia Henzel, Mannheim, DE;

Thomas K. Kessler, Schifferstadt, DE;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/32 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 47/32 (2013.01); A61K 9/2018 (2013.01); A61K 9/2027 (2013.01); A61K 9/2077 (2013.01); A61K 9/2095 (2013.01);
Abstract

A pharmaceutical dosage form comprises a solid dispersion product of at least one active ingredient dispersed in a polymeric binder composition, the polymeric carrier composition comprising a) a vinylpyrrolidone homopolymer, wherein at least 95% by weight of the vinylpyrrolidone homopolymer has a molecular weight distribution within the range of from 1000 to 13 000; and b) a vinylpyrrolidone copolymer having a weight-average molecular weight of from 5000 to 1 500 000. The dosage form is preferably prepared by a melt extrusion process. The polymeric carrier composition exhibits a high drug dissolution power and allows a reduction of the viscosity of the melt without deteriorating the mechanical properties and storage stability of the dosage form.


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