The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2016
Filed:
Apr. 11, 2011
Jonathan M. Austyn, Oxford, GB;
Dermot M. O'hare, Oxford, GB;
Bart Lambrecht, Ghent, BE;
ISIS INNOVATION LTD., Oxford, GB;
UNIVERSITEIT GENT, Ghent, BE;
Abstract
The invention provides a long range ordered, layered double hydroxide compound for use in modulating an immune response to an antigen, and an immune modulator composition comprising the layered double hydroxide and an interlayer anion A. The compound is [MM(OH)][A], in which Mis a divalent metal cation or a mixture of two or more divalent metal cations, Mis a trivalent metal cation or a mixture of two or more trivalent meta cations, or a mixture of one or more trivalent metal cation with one or more quadravalent metal cation, x is from 2:1 to 1:4, and A is an interlayer anion having a charge n, wherein optionally some or all of the interlayer anion A may be replaced by one or biologically active agent and/or one or more antigen, and wherein A is selected from conjugate bases of acids having a pKa of −4 or higher.