The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2016
Filed:
Dec. 29, 2011
Applicant:
Andrew Macadam, Potters Bar, GB;
Inventor:
Andrew MacAdam, Potters Bar, GB;
Assignee:
The Secretary of State for Health, London, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/105 (2006.01); C07K 14/085 (2006.01); A61K 39/13 (2006.01); A61K 39/125 (2006.01); C12N 15/43 (2006.01); C12N 15/41 (2006.01); C12N 7/00 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/13 (2013.01); A61K 39/12 (2013.01); A61K 39/125 (2013.01); C12N 7/00 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/5256 (2013.01); C12N 2770/32011 (2013.01); C12N 2770/32611 (2013.01); C12N 2770/32621 (2013.01); C12N 2770/32634 (2013.01); C12N 2770/32662 (2013.01); G01N 2333/085 (2013.01);
Abstract
The invention provides an attenuated polio virus having a 5' non-coding region consisting of the 5′ non-coding region of Sabin 3, modified so that it does not have a base pair mismatch in stem (a) or (b) of domain V, wherein seven or eight of the base pairs in stems (a) and (b) are U-A or A-U base pairs; and a capsid protein from the Sabin 1, Mahoney, MEF or Saukett strain.