The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2016

Filed:

Apr. 08, 2010
Applicants:

Tingchao Chen, Monterey Park, CA (US);

Yi Zhao, South Pasadena, CA (US);

W. French Anderson, San Marino, CA (US);

Inventors:

Tingchao Chen, Monterey Park, CA (US);

Yi Zhao, South Pasadena, CA (US);

W. French Anderson, San Marino, CA (US);

Assignee:

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); C07K 14/54 (2006.01); A61P 35/02 (2006.01); A61P 7/06 (2006.01); A61K 45/06 (2006.01); A61N 5/10 (2006.01); A61K 31/675 (2006.01);
U.S. Cl.
CPC ...
A61K 38/208 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); C07K 14/5434 (2013.01); A61N 5/10 (2013.01); A61N 2005/1098 (2013.01);
Abstract

Methods for enhancing or stimulating hematopoiesis including the step of administering Interleukin-12 (IL-12) to yield hematopoietic recovery in a mammal in need. Preferred methods include the step of administering IL-12 as an adjuvant therapy to alleviate the hematopoietic toxicities associated with one or more treatment regimens used to combat a disease state. Other methods include administering IL-12 to ameliorate various hematopoietic deficiencies. Still other methods are directed to uses of IL-12 for in-vivo proliferation of hematopoietic repopulating cells, hematopoietic progenitor cells and hematopoietic stem cells. Other disclosed methods are directed to uses of IL-12 for bone marrow preservation or recovery.


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