The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2016
Filed:
Jan. 09, 2015
Applicant:
University Health Network, Toronto, CA;
Inventors:
Guohua Pan, Oakville, CA;
Jacqueline M. Mason, Toronto, CA;
Xin Wei, Markham, CA;
Miklos Feher, New York, NY (US);
Assignee:
University Health Network, Toronto, CA;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/553 (2006.01); A61K 31/00 (2006.01); A61K 31/535 (2006.01); C07D 273/00 (2006.01); C07D 211/00 (2006.01); A61K 31/416 (2006.01); A61K 31/4439 (2006.01); A61K 31/497 (2006.01); A61K 31/495 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
A61K 31/416 (2013.01); A61K 31/4439 (2013.01); A61K 31/495 (2013.01); A61K 31/496 (2013.01); A61K 31/497 (2013.01); A61K 31/5377 (2013.01);
Abstract
Provided herein are methods and compositions for treating a patient with cancer wherein the cancer is characterized by a PTEN gene mutation and/or a PI3K gene mutation. In particular embodiments, the methods comprise administering to the patient a composition comprising a therapeutically effective amount of a PLK4 antagonist.