The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 26, 2016
Filed:
Dec. 31, 2013
Applicants:
Pusan National University Industry-university Cooperation Foundation, Pusan, KR;
The Industry & Academic Cooperation IN Chungnam National University, Daejeon, KR;
Inventors:
Bum Joon Park, Busan, KR;
Nam Chul Ha, Busan, KR;
Sun Hye Lee, Busan, KR;
Gyu Yong Song, Daejeon, KR;
Jee Hyun Lee, Daejeon, KR;
Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); A61K 31/00 (2006.01); C07K 14/00 (2006.01); A61K 31/10 (2006.01); A61K 31/122 (2006.01); C07C 317/44 (2006.01); C07C 323/52 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5748 (2013.01); A61K 31/10 (2013.01); A61K 31/122 (2013.01); C07C 317/44 (2013.01); C07C 323/52 (2013.01); C07C 2102/10 (2013.01);
Abstract
Provided are compounds for inhibiting Snail-p53 binding and therapeutic agents for cancer including the compounds as an effective component. The Snail-p53 binding inhibitors induce expression of p53 in K-Ras mutant cell lines, thereby enabling effective treatment or prevention of K-Ras mutant cancer, such as, pancreatic cancer, lung cancer, cholangioma, and colon cancer, of which diagnosis or treatment is not easy.