The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 26, 2016

Filed:

Dec. 26, 2013
Applicant:

Iowa State University Research Foundation, Inc., Ames, IA (US);

Inventors:

Basil J. Nikolau, Ames, IA (US);

Marna Yandeau-Nelson, Ames, IA (US);

Fuyuan Jing, Ames, IA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/16 (2006.01); C12N 1/20 (2006.01); C12N 1/12 (2006.01); C07H 21/04 (2006.01); C12P 7/64 (2006.01);
U.S. Cl.
CPC ...
C12N 9/16 (2013.01); C12P 7/6409 (2013.01); C12Y 301/02014 (2013.01); C07K 2319/00 (2013.01); Y02P 20/52 (2015.11);
Abstract

A method of increasing production of fatty acids comprising introducing into a host and expressing therein an acyl-acyl carrier protein (ACP) thioesterase (TE) fromor a mutant thereof; a method of making a mutantacyl-ACP TE; a method of making a chimericacyl-ACP TE; a nucleic acid molecule comprising a nucleotide sequence encoding a mutant acyl-ACP TE or a chimericacyl-ACP TE; a host comprising the nucleic acid molecule; a mutant acyl-ACP TE or chimericacyl-ACP TE; a method of altering the specificity of a plant acyl-ACP TE for at least one of its substrates comprising introducing into the plant acyl-ACP TE a substrate specificity-altering mutation; and a method of altering the level of activity of a plant acyl-ACP TE.


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