The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 26, 2016
Filed:
Sep. 29, 2011
Applicants:
Jan Anderl, Modautal, DE;
Werner Simon, Hueffelsheim, DE;
Christoph Mueller, Birkenau, DE;
Inventors:
Assignee:
Heldelberg Pharma GmbH, Ladenburg, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); C07K 16/30 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 47/48415 (2013.01); A61K 47/48561 (2013.01); A61K 47/48569 (2013.01); A61K 47/48584 (2013.01);
Abstract
The invention relates to tumor therapy. In one aspect, the present invention relates to conjugates of an amatoxin and a target-binding moiety, e.g. an antibody, connected by a linker comprising a urea moiety, which are useful in the treatment of cancer. In a further aspect the invention relates to pharmaceutical compositions comprising such conjugates.