The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9399624 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 26, 2016

Filed:

Apr. 17, 2015
Applicants:

Shanghai Jingxin Biomedical Co., Ltd., Shanghai, CN;

Shangyu Jingxin Pharmaceutical Co., Ltd., Shangyu, Zhejiang, CN;

Inventors:

Yue Huang, Shanghai, CN;

Fei Zheng, Shanghai, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/06 (2006.01); C07D 453/02 (2006.01);
U.S. Cl.
CPC ...
C07D 217/06 (2013.01); C07D 453/02 (2013.01);
Abstract

A process for preparation of (1S)-1-phenyl-3,4-dihydro-2(1H)-isoquinoline-carboxylate (Formula I), comprising reacting (1S)-1-phenyl-3,4-dihydro-2(1H)isoquinoline (Formula II) with carbon dioxide and an alkylating agent R-LG in the presence of a base to obtain the compound of Formula I in an organic solvent. In Formula I and II, R is an alkyl or a substituted alkyl; LG is a leaving group.


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Huang, Yue. (2016). Process for preparing (1s)-1-phenyl-3,4-dihydro-2(1h)-isoquinoline-carboxylate (U.S. Patent No. 9399624). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9399624

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