The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 26, 2016

Filed:

May. 27, 2012
Applicants:

Hesaam Esfandyarpour, Redwood City, CA (US);

Kosar B. Parizi, Redwood City, CA (US);

Mark F. Oldham, Emerald Hills, CA (US);

Inventors:

Hesaam Esfandyarpour, Redwood City, CA (US);

Kosar B. Parizi, Redwood City, CA (US);

Mark F. Oldham, Emerald Hills, CA (US);

Assignee:

GENAPSYS, INC., Redwood City, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); B01L 3/00 (2006.01); B03C 1/28 (2006.01); B03C 5/00 (2006.01); B03C 5/02 (2006.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); B03C 1/288 (2013.01); B03C 5/005 (2013.01); B03C 5/026 (2013.01); B01L 7/52 (2013.01); B01L 2200/0668 (2013.01); B01L 2300/089 (2013.01); B01L 2300/0816 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/0418 (2013.01); B01L 2400/0421 (2013.01); B01L 2400/0427 (2013.01); B01L 2400/0655 (2013.01); B03C 2201/26 (2013.01);
Abstract

Aspects of the invention include methods for improving the accuracy and read length of sequencing reactions by utilizing unlabeled unincorporable nucleotides, or by rephasing colony based sequencing reactions. Other aspects include systems and devices for improved measurement of biological reactions associated with bead which may be removed, utilizing current measurement methods through the counter ions associated with said beads due to the presence of reactants bound or associated with said bead, wherein electrodes for generating and measuring said current may be within the Debye length of said bead. Other aspects of the invention include methods for determining concentrations of input samples, means for reuse of an array, methods and apparatus for separating beads with different charge levels from each other.


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