The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 26, 2016

Filed:

May. 28, 2014
Applicants:

International Business Machines Corporation, Armonk, NY (US);

Agency for Science, Technology and Research, Singapore, SG;

Inventors:

Wei Cheng, Singapore, SG;

Xin Ding, Singapore, SG;

Jeannette M. Garcia, San Jose, CA (US);

James L. Hedrick, Pleasanton, CA (US);

Chuan Yang, Singapore, SG;

Yi Yan Yang, Singapore, SG;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); A01N 37/44 (2006.01); A61K 31/785 (2006.01); C08G 73/02 (2006.01); A01N 37/46 (2006.01); A01N 33/04 (2006.01); A01N 47/30 (2006.01);
U.S. Cl.
CPC ...
A61K 31/785 (2013.01); A01N 33/04 (2013.01); A01N 37/46 (2013.01); A01N 47/30 (2013.01); C08G 73/0226 (2013.01);
Abstract

Antimicrobial, non-hemolytic cationic polyamines were prepared by treating partially N-acylated polyethylenimines and/or partially oxidized polyethylenimines with a protic acid. The cationic polyamines can have a linear or branched polyethylenimine backbone structure. Preferably, the cationic polyamines comprise pendant urea groups, which can be introduced via a cyclic carbonate comprising a pendant urea group. The cationic polyamines can be active against a tuberculosisat low concentration. The cationic polyamines are also effective against Gram-negativeand, Gram-positive, and fungusin solution and in the form of a film.


Find Patent Forward Citations

Loading…