The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 26, 2016
Filed:
Jul. 03, 2013
Sbi Pharmaceuticals Co., Ltd., Minato-ku, Tokyo, JP;
National Center for Child Health and Development, Setagaya-ku, Tokyo, JP;
Tohru Tanaka, Tokyo, JP;
Motowo Nakajima, Tokyo, JP;
Fuminori Abe, Tokyo, JP;
Naomi Haga, Tokyo, JP;
Kiwamu Takahashi, Tokyo, JP;
Hidenori Ito, Tokyo, JP;
Ko Rii, Tokyo, JP;
SBI Pharmaceuticals Co., Ltd., Tokyo, JP;
National Center for Child Health and Development, Tokyo, JP;
Abstract
An object of the present invention is to provide a regulatory dendritic cell inducing agent applicable to the treatment of immune disease as well as an immune tolerance inducing agent such as a preventive and/or therapeutic agent for allergic disease and a preventive and/or therapeutic agent for autoimmune disease, both of which are safe and have the mechanism of action different from that of conventional drugs. As a means for achieving the above object, an immune tolerance inducing agent comprising 5-aminolevulinic acid (ALA) or a derivative thereof, or a salt of the 5-ALA or the derivative and an iron compound as active ingredients is prepared. Preferable examples of the ALAs can include ALA and various esters such as methyl ester, ethyl ester, propyl ester, butyl ester, and pentyl ester of ALA, and their hydrochlorides, phosphates, and sulfates. Preferable examples of the iron compound can include sodium ferrous citrate.