The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 26, 2016

Filed:

Dec. 13, 2012
Applicant:

Pharmacophotonics, Inc., Indianapolis, IN (US);

Inventors:

Exing Wang, Carmel, IN (US);

Daniel Meier, Indianapolis, IN (US);

Robert Bunch, Terre Haute, IN (US);

Bruce Molitoris, Indianapolis, IN (US);

Ruben Sandoval, Indianapolis, IN (US);

Matthew Rubin, Indianapolis, IN (US);

Assignee:

Pharmacophotonics, Inc., Indianapolis, IN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/1455 (2006.01); A61B 5/20 (2006.01); A61B 5/00 (2006.01); A61K 49/00 (2006.01); A61B 1/00 (2006.01); A61M 5/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/201 (2013.01); A61B 1/00154 (2013.01); A61B 1/00165 (2013.01); A61B 5/0071 (2013.01); A61B 5/0084 (2013.01); A61B 5/412 (2013.01); A61B 5/6852 (2013.01); A61K 49/0017 (2013.01); A61M 5/007 (2013.01);
Abstract

A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a marker molecule relative to a fluorescence of a reporter molecule.


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