The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9395360 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 19, 2016

Filed:

Oct. 21, 2013
Applicant:

National University of Singapore, Singapore, SG;

Inventors:

Dieter Trau, Singapore, SG;

Wen-Tso Liu, Singapore, SG;

Kian Kok Johnson Ng, Singapore, SG;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); C40B 60/02 (2006.01); G06T 7/00 (2006.01); G06T 5/50 (2006.01); B01J 19/00 (2006.01); C40B 30/04 (2006.01); C40B 40/04 (2006.01); G01N 21/64 (2006.01); C40B 20/02 (2006.01); C12Q 1/68 (2006.01); C40B 50/16 (2006.01); C40B 60/14 (2006.01); C40B 50/18 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54313 (2013.01); B01J 19/0046 (2013.01); C12Q 1/6834 (2013.01); C12Q 1/6883 (2013.01); C40B 20/02 (2013.01); C40B 30/04 (2013.01); C40B 40/04 (2013.01); G01N 21/6452 (2013.01); G06T 5/50 (2013.01); G06T 7/0008 (2013.01); G06T 7/0028 (2013.01); B01J 2219/0054 (2013.01); B01J 2219/0074 (2013.01); B01J 2219/00317 (2013.01); B01J 2219/00459 (2013.01); B01J 2219/00466 (2013.01); B01J 2219/00648 (2013.01); B01J 2219/00659 (2013.01); B01J 2219/00677 (2013.01); B01J 2219/00702 (2013.01); B01J 2219/00722 (2013.01); C40B 50/16 (2013.01); C40B 50/18 (2013.01); C40B 60/14 (2013.01);
Abstract

A process for making a micro-array. The process comprises the step of depositing a population of microbeads on a substrate having at least one fiducial. The population being comprised of at least two sub-populations, preferably multiple sub-populations, each comprising a known active agent capable of specific binding with at least one target analyte. The said subpopulations are deposited sequentially and at discrete periods of each other. The process also comprises the step of making images of the substrate after deposition of each subpopulation. The images are then compared using the fiducial as a reference to thereby determine the location of each microbead and to identify the subpopulation, and its known active agent, based on differences between each image. Also disclosed in a system for using the microarray.


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