The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2016

Filed:

Mar. 12, 2013
Applicant:

Hanmi Science Co., Ltd., Hwaseong-si, Gyeonggi-do, KR;

Inventors:

Yong Ho Huh, Seoul, KR;

Euh Lim Oh, Seoul, KR;

Sung Youb Jung, Suwon-si, KR;

Se Chang Kwon, Seoul, KR;

Assignee:

HANMI SCIENCE CO., LTD, Hwaseong-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/04 (2006.01); C12N 1/20 (2006.01); C12P 21/00 (2006.01); C12P 21/06 (2006.01); C12N 15/74 (2006.01);
U.S. Cl.
CPC ...
C12P 21/00 (2013.01); C12N 1/20 (2013.01);
Abstract

Disclosed is a method of culturingcells for high density, comprising a cell growth step and an expression induction step by which a maximum of cell mass can be obtained with the concomitant maximum expression of a recombinant protein.transformed to produce a recombinant protein of interest can be grown at a high concentration using the culturing method of the present invention. Therefore, the method increases the productivity of cells as well as the production yield of the recombinant protein, and can be widely applied to the effective production of recombinant proteins.


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